Is there any link between Hypothyroidism and Depression?

Is there any link between Hypothyroidism and Depression? The link between hypothyroidism and depression has long been recognised. One explanation for the link between hypothyroidism and depression is the influence of triiodothyronine (T3). T3 is normally concentrated in the area of the brain that controls emotions such as joy, anger and fear. Read on to find out more.
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The link between hypothyroidism and depression has long been recognised. Back in 1969 researchers reported ‘clinical symptoms may mimic that of melancholic depression and dementia’.


Depression is More Than Feeling sad


Feeling sad or disappointed at times is a normal reaction to the challenges of everyday life. However when it comes to depression this condition is associated with more than general feelings of sadness.


Depression leads to feelings of pessimism and ongoing despair.


Individuals with depression suffer in many areas of their lives. It interferes with their ability to cope with everyday life. In addition, they often feel disconnected from their friends and family.


The link between your emotional health and hypothyroidism


Emotional health problems such as depression, anxiety, and post-natal depression may be due to an underlying thyroid issue.


Hypothyroidism occurs when there is low production, or reduced activity of the thyroid hormones. Hypothyroidism, especially when coupled with adrenal fatigue, gives rise to a diverse range of emotional health problems. Many individuals with a thyroid-adrenal imbalance also experience depression.


The symptoms that help identify depression include:


  • Feeling hopeless about life.
  • A lack of interest in daily activities.
  • Anger or irritability.
  • Memory and concentration problems.
  • Appetite or weight changes.
  • Sleep changes.
  • Feeling physically drained.
  • Feelings of not being worthy.
  • Addictions and addictive behaviour.
  • Unexplained muscle aches and headaches


Low T3 + mood


One explanation for the link between hypothyroidism and depression is the influence of triiodothyronine (T3). T3 is normally concentrated in the area of the brain that controls emotions such as joy, anger and fear.


T3 plays an important role in regulating activity of the three ‘feel good’ neurotransmitters. These neurotransmitters have a powerful effect on your emotions. These key neurotransmitters include serotonin, noradrenaline and GABA (gamma-aminobutyric acid).


Serotonin and noradrenaline are often referred to as the ‘happy’ messengers. They boost your mood. Serotonin also helps regulate sleep and hunger.


Chronic stress can lower both serotonin and noradrenaline production. GABA is often referred to as the ‘calming’ messenger. It helps keep you relaxed and focused.


T3 regulates the action of serotonin, adrenaline and GABA. If you do not have enough T3, or the action is blocked, production of these neurotransmitters can be affected.


Could it be hypothyroidism?


Individuals with depression, anxiety, or some type of serious psychiatric illness should be screened for hypothyroidism.


According to the American Association of Clinical Endocrinologists, “The diagnosis of subclinical, or clinical hypothyroidism must be considered in every patient with depression’.


It’s possible an individual could experience a significant shift in their mood, and cognitive function if an underlying thyroid disorder is addressed.


SPECIAL NOTE: This ‘Hypothyroidism and Depression’ article is for educational purposes to assist you in living well. It should not be used as a substitute for the advice provided by your medical practitioner.


If you suspect you are experiencing depression, promptly seek professional advice. Do not cease taking your prescribed medication without the consent of your medical doctor.


Watch the following videos


Hypothyroidism And Depression Connection


How to Fight Depression and Anxiety Caused By Hypothyroidism

Read the following related articles:


10 Hypothyroidism Diet Tips to Help Heal Your Thyroid


Warnings: 4 Types of Toxic Cookware to Avoid & Why


What is really The Best Cooking Oil for Thyroid Health?


5 Important Steps for Hypothyroidism Treatment Success


Hormone Problem? Here’s Your Hormone Imbalance Checklist


Are Iodine Supplements For Thyroid Health Really Safe?


What is Hashimoto’s Thyroiditis?


Skin Deep. Do Cosmetics Harm the Thyroid?


What is the Best Way to Diagnose Hypothyroidism?


Can Basal Temperature Testing Help Diagnosis A Thyroid Problem?


Should You Get a T3 Test If You Find It Hard to Lose Weight?


Why Knowing How to Calculate Your Reverse T3 Ratio Helps to Assess Overall Thyroid Health?


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Why Soy Foods Should Be Avoided if You Have Thyroid Disorder?


Why Cruciferous Vegetables Should Be Strictly avoided if you have Thyroid Problems?


Why Trans Fats are Harmful for Your Thyroid?


Author Bio:


Louise O’ Connor, the author of The Natural Thyroid Diet –The 4-Week Plan to Living Well, Living Vibrantly, who is a specialist in Thyroid Health. She is a highly regarded Australian Naturopath and founder of Wellnesswork.


The Natural Thyroid Diet goes beyond diet advice and offers practical and effective ways to achieve healthy thyroid levels within just a short period of time. For more details, Click on

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